Cultured muscle cells display defects of mitochondrial myopathy ameliorated by anti-oxidants
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چکیده
منابع مشابه
Cultured muscle cells display defects of mitochondrial myopathy ameliorated by anti-oxidants.
The mitochondrial DNA A3243G mutation causes neuromuscular disease. To investigate the muscle-specific pathophysiology of mitochondrial disease, rhabdomyosarcoma transmitochondrial hybrid cells (cybrids) were generated that retain the capacity to differentiate to myotubes. In some cases, striated muscle-like fibres were formed after innervation with rat embryonic spinal cord. Myotubes carrying ...
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ژورنال
عنوان ژورنال: Brain
سال: 2007
ISSN: 0006-8950,1460-2156
DOI: 10.1093/brain/awm151